Dr. Stephen F. Badylak holds material extracted from pig intestine that would be used to
replace damaged human ligaments in a 1997 file photo.
replace damaged human ligaments in a 1997 file photo.
Scientists Develop Powder to Regrow Limbs
May 01, 2008 4:50 PM
by
findingDulcinea Staff
Limb regeneration is looking more feasible, as scientists say that they have developed a powder that can help to regrow severed fingers.
30-Second Summary
Hobby shop worker Lee Spievak, 69, says that his severed fingertip grew back in four weeks after applying a powder supplied by Dr. Stephen Badylak, an expert in regenerative medicine.
Badylak says the powder causes cells to regenerate and that it brings doctors a step closer to creating and replacing complex organs or even entire limbs, such as arms and legs. Currently, scientists can grow simple tissues like skin, cartilage, bladders, ears, noses, blood vessels and other body parts, according to Discovery News.
Professor Stephen Kaye, a surgeon at Leeds University, points out in Britain’s Daily Mail that Spievak’s finger did not suffer any bone, nerve or tendon loss and simply had to repair skin. “The pictures I’ve seen on the Web show a wound I would have expected to heal and regenerate in any case,” Kaye said.
Whatever is responsible for Spievak’s regrown fingertip, researchers continue to forge ahead in studying limb regeneration. The Pentagon has embarked on a new five-year, $250 million regenerative medicine project aimed at healing soldiers and civilians.
In a recent article, Scientific American magazine outlines studies of salamanders, considered the “gold standard” for limb regeneration in the animal world, and offers a positive assessment of the field’s future.
“Indeed, when we consider all that we have learned about wound healing and regeneration from studies in various animal models, the surprising conclusion is that we may be only a decade or two away from a day when we can regenerate human body parts,” concludes the magazine.
Badylak says the powder causes cells to regenerate and that it brings doctors a step closer to creating and replacing complex organs or even entire limbs, such as arms and legs. Currently, scientists can grow simple tissues like skin, cartilage, bladders, ears, noses, blood vessels and other body parts, according to Discovery News.
Professor Stephen Kaye, a surgeon at Leeds University, points out in Britain’s Daily Mail that Spievak’s finger did not suffer any bone, nerve or tendon loss and simply had to repair skin. “The pictures I’ve seen on the Web show a wound I would have expected to heal and regenerate in any case,” Kaye said.
Whatever is responsible for Spievak’s regrown fingertip, researchers continue to forge ahead in studying limb regeneration. The Pentagon has embarked on a new five-year, $250 million regenerative medicine project aimed at healing soldiers and civilians.
In a recent article, Scientific American magazine outlines studies of salamanders, considered the “gold standard” for limb regeneration in the animal world, and offers a positive assessment of the field’s future.
“Indeed, when we consider all that we have learned about wound healing and regeneration from studies in various animal models, the surprising conclusion is that we may be only a decade or two away from a day when we can regenerate human body parts,” concludes the magazine.
Headline Links: ‘“Pixie dust” brings scientists closer to growing limbs’
Spievak injured his finger in an accident with a toy plane. Badylak developed the powder by experimenting with cells extracted from pig intestines, which were dried up and made into a powder.
Source: ABC News
The Daily Mail’s coverage of the powder includes a diagram called “How to regrow a severed finger.” Professor Stephen Kaye, a consultant plastic and hand surgeon at Leeds University, was skeptical of Spievack’s claims. “The end of the finger is extremely good at regeneration. The pictures we’ve seen on the Web show no evidence of loss of bone, nerve or tendon material, but regeneration and repair of skin—which is exactly what the fingertip does.”
Source: The Daily Mail
Related Topics: New Pentagon initiative, research on salamanders
The Defense Department has embarked on a five-year, $250 million project to heal soldiers and civilians through regenerative medicine. “Humans can regenerate ourselves, but only up to a certain point,” said Anthony Atala, a doctor at Wake Forest University. “The concept here is using not just the cells you have under normal conditions, but also using outside techniques to help speed up the natural regeneration process.”
Source: Discovery
A recent Scientific American article asks whether people can regrow body parts “salamander-style,” and examines recent research on the amphibian. Salamanders are capable of growing perfect replacements of lost body parts throughout their lives.
Source: Scientific American
Background: ‘An eary tale’
In 1995, doctors caused a stir when they grew a human ear on the back of a live mouse, which was created by scientists at the University of Massachusetts and the Massachusetts Institute of Technology. It was a dramatic example of progress in tissue engineering at the time, and it was predicted that in the future humans would be able to grow tissue without the help of mice.
Source: Time
Audio: ‘Regrowing human limbs’
Word of Mouth host Virginia Prescott chats with John Rennie, the editor-in-chief of Scientific American, about limb regeneration.



