Chronic Lymphocytic Leukemia
Chronic lymphocytic leukemia, also known as CLL, is a type of cancer that develops very slowly in the bone marrow. Use this Web guide to learn more about CLL, how it’s diagnosed and treated, and where to find support.
What is Chronic Lymphocytic Leukemia?
When a person has chronic lymphocytic leukemia, the bone marrow makes too many lymphocytes, a type of white blood cell. The cancerous lymphocytes crowd out other types of healthy blood cells, causing problems such as anemia, easy bleeding and infection.
Dulcinea's Insight
- According to the Cleveland Clinic, chronic lymphocytic leukemia is the second most common leukemia diagnosed in adults.
- Although CLL is very rarely diagnosed in children, acute lymphoblastic leukemia (ALL) is. Learn more about ALL with the findingDulcinea Acute Lymphoblastic Leukemia Web Guide.
Dulcinea's Picks
For an overview of CLL …
The College of American Pathologists
offers a comprehensive overview of chronic lymphocytic leukemia, a slow-growing disease that is most often seen in middle-aged men, those who have had cancer of the lymphatic system, and descendants of Russian or Eastern European Jews.
The Leukemia & Lymphoma Society
provides a straightforward description of CLL that includes causes and risk factors.
For CLL’s signs and symptoms …
Mayo Clinic
lists the signs and symptoms of chronic lymphocytic leukemia, and explains that they are often mild and vague at the beginning of the disease.
For causes …
The American Cancer Society
has an in-depth article that explains basic genetics and how chromosomal changes are thought to contribute to the development of CLL.
Chronic Lymphocytic Leukemia Diagnosis and Treatment
A variety of treatment options exist for CLL, ranging from chemotherapy to stem cell transplants. Learn more about conventional and experimental treatments using the sites below.
Dulcinea's Insight
- Unlike other types of leukemia, a person could have chronic lymphocytic leukemia for years before developing symptoms or even needing treatment, according to Memorial Sloan-Kettering Cancer Center.
- If you conduct Web research on CLL beyond this guide, be aware that many sites profess to provide credible medical information but are sponsored by law firms interested only in finding clients. The Web sites listed in this guide are all maintained by respected health care organizations or are sites created by patients based on their own experiences.
Dulcinea's Picks
For CLL diagnosis …
WebMD
describes the tests used to diagnose chronic lymphocytic leukemia, and explains the different stages of CLL.
For treatment …
National Cancer Institute
discusses the different treatment options for CLL, such as “watchful waiting,” removing the spleen, radiation therapy, chemotherapy and more.
For clinical trials …
ClinicalTrials.gov
is a clearinghouse operated by the U.S. National Institutes of Health that lists clinical trials currently underway to research CLL. To learn more about clinical trials, speak to your doctor and read the U.S. Food and Drug Administration's guide.
Support for Chronic Lymphocytic Leukemia
The Web makes it easy to connect with others who have been affected by CLL. Use the blogs, message boards and forums in this section to interact with other CLL patients, survivors and their families.
Dulcinea's Insight
- There aren’t many blogs about women with chronic lymphocytic leukemia on the Web, possibly because the cancer is diagnosed more often in men.
- To find even more support sites, see the “Support Groups for Leukemia Patients” section of the findingDulcinea Leukemia Web Guide.
Dulcinea's Picks
For managing CLL…
CLL Topics
is a nonprofit organization offering patient support and information. Read “A CLL Primer” to find tips for the patient who has been recently diagnosed.
CLL Support Association
, a support group based in the U.K., has a page with suggestions for different aspects of life with CLL, such as traveling, eating and interacting with children.
For face-to-face support groups …
The Leukemia & Lymphoma Society
provides a PDF guide for CLL patients and caregivers, and lists contact information for local Society chapters by state (scroll down to find the list). For family support groups near you, the site asks you to contact your local Society chapter. To find support groups in Canada, visit the Society’s Canadian site.
For blogs …
CLL Diary
is a blog written by a man in his 50s who has chronic lymphocytic leukemia. Read about his life and how he copes with CLL. Scroll down the page for a list of acronyms commonly used when discussing the disease.
How’s Dave Doing
is a blog “for family and friends” of a man with CLL, written mostly by his wife. The posts talk about his progress with the disease and their life together.
For patients’ stories …
CLL Support Association
has a number of resources for people with chronic lymphocytic leukemia. Visit this page for stories of how patients were diagnosed and treated, and their thoughts on having CLL.
For forums …
CLL Forum
has several active discussion threads where people can talk about being diagnosed and their treatment progress, as well as find emotional support. One thread is just for caregivers.







