Acute Myelogenous Leukemia
Acute Myelogenous Leukemia, known as Acute Myeloid Leukemia, or AML, is a fast-growing cancer that starts in the bone marrow or other blood-forming tissue and spreads into the bloodstream. It is the most common type of leukemia.
AML is a type of cancer in which immature stem cells that normally mature into normal red or white blood cells or platelets, instead develop into a type of abnormal white blood cell that reproduces rapidly and crowds out the desirable blood cells. While most AML patients are adults, with an average patient age over 65, AML is also one of the most common cancers in infants and toddlers. According to the American Cancer Society, 13,290 new cases are expected in 2008.
- In adults, AML has been linked to exposure to the chemical benzene. Many Web sites you encounter in search engines profess to provide credible medical information but are sponsored by law firms interested only in finding clients. The Web sites included in this guide are all sponsored by respected health care organizations.
For an overview of AML …
Mayo Clinic
offers a brief introduction to acute myelogenous leukemia, and explains the meaning of each portion of the condition’s name.
National Marrow Donor Program
provides a well-written overview of AML, offering a more in-depth description of the types of cells affected and their function.
eMedicine
offers a comprehensive explanatory article about AML, geared towards physicians.
For AML’s signs and symptoms …
Mayo Clinic
lists the symptoms a person with AML can experience, including weight loss, bone pain, fatigue and fever.
Acute myelogenous leukemia is treated in a number of ways, and adults are treated differently than children. Investigators are also pursuing a number of new, experimental approaches. According to the Leukemia and Lymphoma Society, “The number of patients with AML who enter remission, stay in remission for years or are cured has increased significantly over the past 30 years.”
For diagnosis …
Adam.com
explains what happens during a bone marrow aspiration, in which part of the marrow is removed so doctors can examine it. Another page describes a similar procedure, a
bone marrow biopsy.
For treating adults …
The National Cancer Institute
briefly describes the two treatment phases for adults with AML, and outlines the four standard treatment options: radiation therapy, medication, chemotherapy and stem cell transplant.
Cancer Backup
is a UK nonprofit that provides cancer information. This page explains the different types of transplants, such as receiving stem cells from a donor or your own.
ClinicalTrials.gov
is a clearinghouse operated by the U.S. National Institutes of Health that provides a list of research clinical trials currently underway to test experimental treatments for AML. To learn more about clinical trials, speak to your doctor, and read the
U.S. Food and Drug Administration’s guide.
For treating children …
The American Cancer Society
describes the treatment procedures for children with AML. The society recommends children get treatment at hospitals with experience in this type of leukemia “because of the intensity of treatment and the risk of serious complications.”
To find a children’s hospital …
CureSearch
has a directory of hospitals that are part of the Children’s Oncology Group, a worldwide group of health professionals dedicated to treating childhood cancer. According to the
American Cancer Society, more than 90 percent of children diagnosed with cancer are treated at these centers.
The National Cancer Institute
answers questions about specialized pediatric cancer centers in the Children’s Oncology Group, their standards and clinical trials.
To find a cancer center for adults …
The National Cancer Institute
has a searchable directory of cancer centers that the agency recognizes for their excellence. Be sure to click on either “Comprehensive Cancer Center” or “Cancer Center” that provides patient services.
For complementary and alternative medicine …
The Leukemia and Lymphoma Society
discusses the use of complementary and alternative medicine (CAM) in this 13-page PDF document. Speak to your doctor before using any CAM, as other treatments could affect your conventional treatment.
A cancer diagnosis, while devastating, should not be isolating. Thousands of people are diagnosed with leukemia each year. Many have chronicled their stories in blogs on the Web, or shared their experiences in forums.
- Few blogs or forums are devoted solely to acute myelogenous leukemia, but there are many sites that discuss leukemia generally that can be good sources of support. Start with the support resources included in the findingDulcinea Leukemia Web Guide.
For blogs …
Leukemia Survivor
is a blog about a 12-year-old girl who was diagnosed with AML in 2006, and how she fought the disease. Scroll down to “Yam’s Story as She Wrote It” on the right side of the page to read her first-person account.
For forums …
The Leukemia and Lymphoma Society
has a discussion board called Living with AML. People post about loved ones who are being treated, or ask about hospitals and treatments.
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